Wednesday, January 2, 2013

A new fish species from Lake Victoria named in honor of the author of Darwin's Dreampond

Jan. 2, 2013 ? Two new species of cichlid fish from Lake Victoria are described by biologists from Naturalis Biodiversity Center (Research Department Marine Zoology) and the Institute of Biology Leiden (Section Integrative Zoology), the Netherlands. One of these species is named in honour of Tijs Goldschmidt, author of Darwin's Dreampond. This book, published in nine languages, describes the dramatic extinction of hundreds of cichlid species in Lake Victoria in the 1980s due to the introduced Nile perch and other human induced environmental changes.

In 1985, Leiden biologists made a survey in the Tanzanian part of the lake, with an old ferry as floating lab, to establish the status of the rapidly declining cichlids. During this expedition Tijs studied the egg spots on the anal fin of cichlids for their possible role in the rapid speciation of these fish. In the Emin Pasha Gulf, among a species nicknamed Haplochromis "argens," individuals were found with aberrant egg dummies and lacking red in the fins. Just the kind of example Tijs was looking for to test his theory of speciation by sexual selection. The aberrant individuals were provisionally named H. "dusky argens."

Both "species" play a part in Tijs' PhD thesis and in other studies. However, a taxonomic description was never made and whether H. "dusky argens" was a separate species or a colour morph remained unclear. In 1987, most cichlid species from the offshore waters of the lake had disappeared, and with them the urge of taxonomic descriptions.

Now, 25 years later, about a quarter of the cichlid species have recovered in the "Nile perch desert," some of them became even more abundant than in the past, but the former common H. "argens" is still extremely rare. The status of H. "dusky-argens" is unknown as it was only caught in the remote Emin Pasha Gulf, which is not sampled nowadays. Research on successfully resurgent species shows that they were able to adapt morphologically to the new environmental conditions. Their body shape, for instance, changed, so that burst swimming to escape predators improved. Preliminary results suggest that such a response is not found in H. "argens."

The above observations triggered the present taxonomic study as a baseline for further research. It shows that several taxonomic characters differ more between the co-occurring populations of H. "argens" and H. "dusky argens" in the Emin Pasha Gulf, than between populations from different locations. This suggests that they are indeed two species, which are morphologically driven apart at places where they co-occur. In case of H. "argens" the nickname was upgraded to the formal name, while H. "dusky-argens" is now named H. goldschmidti.

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The above story is reprinted from materials provided by Pensoft Publishers, via EurekAlert!, a service of AAAS.

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Journal Reference:

  1. Marnix de Zeeuw, Irene Westbroek, Martien van Oijen, Frans Witte. Two new species of zooplanktivorous haplochromine cichlids from Lake Victoria, Tanzania. ZooKeys, 2013; 256 (0): 1 DOI: 10.3897/zookeys.256.3871

Note: If no author is given, the source is cited instead.

Disclaimer: Views expressed in this article do not necessarily reflect those of ScienceDaily or its staff.

Source: http://feeds.sciencedaily.com/~r/sciencedaily/most_popular/~3/f0eIpakDCGA/130102111620.htm

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Recreation-and-Sports Nautical Sayings And Phrases - obautaka ...

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Travel-and-Leisure Part 2 - The Southern Area - Dover To Sole 05th January 2012 The shipping forecast is a an informative broadcast of the sea areas and weather conditions. Broadcast daily on Radio 4 it is on at 2300, 0500,1100 and 1700 GMT. It provides precise detail on gale warnings, wind direction, visibility and overall weat... Read > Recreation-and-Sports Sea Areas of the Shipping Forecast 04th January 2012 Part 1. The Eastern Area - Viking to Thames "Forties, Cromarty, Forth, Tyne, Dogger, Fisher, German Bight" - such evocative sounds, but where do they come from and why? A bit of history: Gale warnings for the British Isles were first broadcast to s... Read > Travel-and-Leisure Part 3 - The Western Area - Lundy To South East Iceland 04th January 2012 The final part of the shipping forecast is the Western Area. From Lundy to the South East of Iceland. One of the other main features of the shipping forecast on gax1d0sda Radio 4 is its infamous intro music 'Sailing By', by Ronald Binge. This music has become ... Read > Recreation-and-Sports Nautical Sayings And Phrases - Everyday Language 19th December 2011 When it comes to being out on the open waters it is not just a fully equipped boat

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Senate's "fiscal cliff" bill adds $4 trillion to deficits: CBO

WASHINGTON (Reuters) - The Congressional Budget Office on Tuesday said Senate-passed legislation to avert the "fiscal cliff" would add nearly $4 trillion to federal deficits over a decade, largely because it would extend low tax rates for almost all Americans.

The congressional scorekeeper's analysis was released as a number of Republicans in the House of Representatives voiced opposition to the bill, and considered amending it with deeper spending cuts.

House Majority Leader Eric Cantor and others complained the bill's spending cuts would do little to curb trillion-dollar deficits.

Senate-passed plan extends decade-old Bush-era tax rates for individuals earning up to $400,000 and couples earning up to $450,000 - nearly 99 percent of U.S. taxpayers.

But the non-partisan CBO compared the Senate plan's revenue and expenditure changes to laws that are currently in force, which call for $600 billion in tax hikes and automatic spending cuts in 2013 alone - effectively a dive off the fiscal cliff.

With Congress feverishly working to avoid the fiscal cliff in recent weeks, many Washington policymakers had viewed the current-law budget "baseline" as unlikely to be maintained.

Compared to an alternative CBO scenario in which Congress extends all expiring tax provisions and turns off automatic spending cuts slated to start taking effect this week, the Senate plan achieves minimal deficit reduction in the early years.

Over 10 years, deficits under the Senate plan would be $3.75 trillion less than permanently extending all of the tax and spending policies in the alternative scenario. That is largely because the CBO expects that remaining on an unsustainable fiscal path would severely constrict economic growth later in the decade, holding back revenue growth and keeping outlays higher.

FISCAL 2013 EFFECTS

By going over the fiscal cliff, the CBO had previously forecast that the higher taxes and lower spending would slash the fiscal 2013 U.S. budget deficit by more than half, to $641 billion from $1.1 trillion the prior year.

But in its analysis of the Senate-passed plan, the CBO said fiscal 2013 revenues would be $280 billion lower and spending $50 billion higher, resulting in a $330 billion deficit increase, for a total deficit of around $971 billion.

Under the CBO's keep-taxes-unchanged scenario, the deficit would be $1.04 trillion for fiscal 2013.

None of the CBO's analyses takes into consideration possible future spending cuts and reforms to federal health care and retirement programs that Congress might make in a new budget battle emerging around mid-February over the next increase in the U.S. debt limit.

(Reporting By Kim Dixon and David Lawder; Editing by David Gregorio and Vicki Allen)

Source: http://news.yahoo.com/cbo-says-senates-fiscal-cliff-bill-adds-4-193928294.html

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Inspirational Quotes to kick off 2013! | Small Business Branding

The CUSBA Linkedin Group had these terrific quotes posted this morning. They were compiled by mycomeup.com I hope you enjoy them as much as I did.

# 1 ? IKEA founder Ingvar Kamprad
?Only those who are asleep make no mistakes.?

# 2 ? Warren Buffett, CEO of Berkshire Hathaway
?Rule no. 1: Never lose money. Rule no. 2: Never forget rule No. 1.?

# 3 ? Steven Jobs, Apple Co-Founder
?You can?t just ask customers what they want and then try to give that to them. By the time you get it built, they?ll want something new.?

# 4 ? Andrew Carnegie, Carnegie Steel Company Founder
?As I grow older, I pay less attention to what men say. I just watch what they do.?

# 5 ? Ingvar Kamprad, IKEA Founder
?Only those who are asleep make no mistakes.?

# 6 ? Aristotle Onassis, Greek Shipping Magnate
?The secret to business is to know something that nobody else knows.?

# 7 ? Carlos Slim Helu, CEO of Telmex, America Movil, Grupo Carso
?When you live for others? opinions, you are dead.?

# 8 ? Sam Walton, Walmart Founder
?We?re all working together; that?s the secret.?

# 9 ? Richard Branson, Chairman of Virgin Group
?We?re going where no one has gone before. There?s no model to follow, nothing to copy. That is what makes this so exciting.?

# 10 ? Oprah Winfrey, CEO of Oprah Winfrey Network
?You become what you believe. You are where you are today in your life based on everything you have believed.?

# 11 ? Ted Turner, CNN Founder
?I just love it when people say I can?t do it, there?s nothing that makes me feel better because all my life, people have said that I wasn?t going to make it.?

# 12 ? J. Paul Getty, Getty Oil Company Founder
?If you can count your money, you don?t have a billion dollars.?

Source: http://www.smallbusinessbranding.com/5300/inspirational-quotes-to-kick-off-2013/

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New Firm Shopping for MHCs | Daily Business News

BizJournals tells MHProNews newly-formed Inspire Communities of Gold River, Calif. intends to be a player on the national MHC scene. Formed when Follett Investment Properties combined forces with American Infrastructure MLP Funds in Foster City, Calif., just south of San Francisco, Matthew Follett, CEO of Inspire says they have already acquired eight MHCs in Michigan, Arizona and Texas. American Infrastructure is a private equity firm and the majority stakeholder in Inspire, which now has $100 million to go shopping for more communities.

(Photo credit: TriStar Estates MHC)

Categories: Business, Communities, Company News, Manufactured Homes, News Item Tags: 100 million, american infrastructure, CEO, follett, foster city, gold river, investment properties, MHC, MHCs, MHProNews, private equity firm, San Francisco, shopping, stakeholder

Source: http://www.mhmarketingsalesmanagement.com/blogs/daily-business-news/new-firm-shopping-for-mhcs/

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Tuesday, January 1, 2013

Differences in generic pill characteristics may lead to interruptions in essential medication use

Differences in generic pill characteristics may lead to interruptions in essential medication use [ Back to EurekAlert! ] Public release date: 31-Dec-2012
[ | E-mail | Share Share ]

Contact: Jessica Maki
jmaki3@partners.org
617-534-1603
Brigham and Women's Hospital

Changes in pill appearance significantly increase the odds that patients will stop taking their drugs as prescribed

Boston, MAGeneric medications currently account for over 70 percent of prescriptions dispensed. However, while generic drugs are clinically bioequivalent to the brand-name version, they often differ in their physical characteristics, such as color and shape. Researchers from Brigham and Women's Hospital (BWH) have found that some patients who receive generic drugs that vary in their color are over 50 percent more likely to stop taking the drug, leading to potentially important and potentially adverse clinical effects.

The study will be published electronically on December 31, 2012 in the Archives of Internal Medicine.

"Pill appearance has long been suspected to be linked to medication adherence, yet this is the first empirical analysis that we know of that directly links pills' physical characteristics to patients' adherence behavior," explained Aaron S. Kesselheim MD, JD, MPH, assistant professor of medicine in the Division of Pharmacoepidemiology and Pharmacoeconomics at BWH, and principal investigator of this study. "We found that changes in pill color significantly increase the odds that patients will stop taking their drugs as prescribed."

The researchers conducted a case-control study of patients taking antiepileptic drugs and compared the odds that patients who did not refill their medication had been given pills that differed in color or shape from the prior prescriptions. Using a large national database of filled prescriptions, when the researchers identified a break in the patient's use of the drug, they looked at the previous two prescription fillings to see if they were the same color and shape. They found that interruptions in the prescription filling occurred significantly more frequently when the pills had different color. Interruptions in antiepileptic drug use for even a few days can raise the risk of seizure and have important medical and social consequences for patients.

These findings offer important take-home messages for physicians, pharmacists, and patients. As Kesselheim explained, "Patients should be aware that their pills may change color and shape, but that even differently-appearing generic drugs are approved by the FDA as being bioequivalent to their brand-name counterparts and are safe to take. Physicians should be aware that changes in pill appearance might explain their patients' non-adherence. Finally, pharmacists should make a point to tell patients about the change in color and shape when they change generic suppliers."

Researchers acknowledge that medication adherence is a multi-faceted issue, but suggest that taking steps to permit (or even require) similarity in pill appearance among bioequivalent brand name and generic drugs may offer a relatively simple way to contribute to better adherence.

###

This research was supported by a career development award from the Agency for Healthcare Research & Quality (K08HS18465-01), and a Robert Wood Johnson Foundation Investigator Award in Health Policy Research. Dr. Choudhry has received unrestricted research grants from CVS Caremark, Aetna, the Commonwealth Fund, and the Robert Wood Johnson Foundation to study medication adherence. Dr. Shrank has received unrestricted research funding from CVS Caremark, Aetna, Teva, Lilly, and the National Association of Chain Drug Stores.

Brigham and Women's Hospital (BWH) is a 793-bed nonprofit teaching affiliate of Harvard Medical School and a founding member of Partners HealthCare. BWH has more than 3.5 million annual patient visits, is the largest birthing center in New England and employs nearly 15,000 people. The Brigham's medical preeminence dates back to 1832, and today that rich history in clinical care is coupled with its national leadership in patient care, quality improvement and patient safety initiatives, and its dedication to research, innovation, community engagement and educating and training the next generation of health care professionals. Through investigation and discovery conducted at its Biomedical Research Institute (BRI), BWH is an international leader in basic, clinical and translational research on human diseases, involving nearly 1,000 physician-investigators and renowned biomedical scientists and faculty supported by nearly $625 million in funding. BWH continually pushes the boundaries of medicine, including building on its legacy in organ transplantation by performing the first face transplants in the U.S. in 2011. BWH is also home to major landmark epidemiologic population studies, including the Nurses' and Physicians' Health Studies, OurGenes and the Women's Health Initiative. For more information and resources, please visit BWH's online newsroom.



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?


AAAS and EurekAlert! are not responsible for the accuracy of news releases posted to EurekAlert! by contributing institutions or for the use of any information through the EurekAlert! system.


Differences in generic pill characteristics may lead to interruptions in essential medication use [ Back to EurekAlert! ] Public release date: 31-Dec-2012
[ | E-mail | Share Share ]

Contact: Jessica Maki
jmaki3@partners.org
617-534-1603
Brigham and Women's Hospital

Changes in pill appearance significantly increase the odds that patients will stop taking their drugs as prescribed

Boston, MAGeneric medications currently account for over 70 percent of prescriptions dispensed. However, while generic drugs are clinically bioequivalent to the brand-name version, they often differ in their physical characteristics, such as color and shape. Researchers from Brigham and Women's Hospital (BWH) have found that some patients who receive generic drugs that vary in their color are over 50 percent more likely to stop taking the drug, leading to potentially important and potentially adverse clinical effects.

The study will be published electronically on December 31, 2012 in the Archives of Internal Medicine.

"Pill appearance has long been suspected to be linked to medication adherence, yet this is the first empirical analysis that we know of that directly links pills' physical characteristics to patients' adherence behavior," explained Aaron S. Kesselheim MD, JD, MPH, assistant professor of medicine in the Division of Pharmacoepidemiology and Pharmacoeconomics at BWH, and principal investigator of this study. "We found that changes in pill color significantly increase the odds that patients will stop taking their drugs as prescribed."

The researchers conducted a case-control study of patients taking antiepileptic drugs and compared the odds that patients who did not refill their medication had been given pills that differed in color or shape from the prior prescriptions. Using a large national database of filled prescriptions, when the researchers identified a break in the patient's use of the drug, they looked at the previous two prescription fillings to see if they were the same color and shape. They found that interruptions in the prescription filling occurred significantly more frequently when the pills had different color. Interruptions in antiepileptic drug use for even a few days can raise the risk of seizure and have important medical and social consequences for patients.

These findings offer important take-home messages for physicians, pharmacists, and patients. As Kesselheim explained, "Patients should be aware that their pills may change color and shape, but that even differently-appearing generic drugs are approved by the FDA as being bioequivalent to their brand-name counterparts and are safe to take. Physicians should be aware that changes in pill appearance might explain their patients' non-adherence. Finally, pharmacists should make a point to tell patients about the change in color and shape when they change generic suppliers."

Researchers acknowledge that medication adherence is a multi-faceted issue, but suggest that taking steps to permit (or even require) similarity in pill appearance among bioequivalent brand name and generic drugs may offer a relatively simple way to contribute to better adherence.

###

This research was supported by a career development award from the Agency for Healthcare Research & Quality (K08HS18465-01), and a Robert Wood Johnson Foundation Investigator Award in Health Policy Research. Dr. Choudhry has received unrestricted research grants from CVS Caremark, Aetna, the Commonwealth Fund, and the Robert Wood Johnson Foundation to study medication adherence. Dr. Shrank has received unrestricted research funding from CVS Caremark, Aetna, Teva, Lilly, and the National Association of Chain Drug Stores.

Brigham and Women's Hospital (BWH) is a 793-bed nonprofit teaching affiliate of Harvard Medical School and a founding member of Partners HealthCare. BWH has more than 3.5 million annual patient visits, is the largest birthing center in New England and employs nearly 15,000 people. The Brigham's medical preeminence dates back to 1832, and today that rich history in clinical care is coupled with its national leadership in patient care, quality improvement and patient safety initiatives, and its dedication to research, innovation, community engagement and educating and training the next generation of health care professionals. Through investigation and discovery conducted at its Biomedical Research Institute (BRI), BWH is an international leader in basic, clinical and translational research on human diseases, involving nearly 1,000 physician-investigators and renowned biomedical scientists and faculty supported by nearly $625 million in funding. BWH continually pushes the boundaries of medicine, including building on its legacy in organ transplantation by performing the first face transplants in the U.S. in 2011. BWH is also home to major landmark epidemiologic population studies, including the Nurses' and Physicians' Health Studies, OurGenes and the Women's Health Initiative. For more information and resources, please visit BWH's online newsroom.



[ Back to EurekAlert! ] [ | E-mail | Share Share ]

?


AAAS and EurekAlert! are not responsible for the accuracy of news releases posted to EurekAlert! by contributing institutions or for the use of any information through the EurekAlert! system.


Source: http://www.eurekalert.org/pub_releases/2012-12/bawh-dig121812.php

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